CATH Domain 2jleA03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.270	Reverse transcriptase/Diguanylate cyclase domain

Domain Context

CATH Clusters

Superfamily	3.30.70.270
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q72547_9HIV1

Human immunodeficiency virus 1

Reverse transcriptase/RNaseH

PDB Structure

PDB	2JLE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays. Jones, L.H., Allan, G., Barba, O., Burt, C., Corbau, R., Dupont, T., Knochel, T., Irving, S., Middleton, D.S., Mowbray, C.E., Perros, M., Ringrose, H., Swain, N.A., Webster, R., Westby, M., Phillips, C. J.Med.Chem.