CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10590 | Zn-dependent exopeptidases |
Domain Context
CATH Clusters
| Superfamily | Zn-dependent exopeptidases |
| Functional Family | Leucine aminopeptidase 1 |
Enzyme Information
| 3.4.11.1 |
Leucyl aminopeptidase.
based on mapping to UniProt P34629
Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.
-!- Is activated by heavy metal ions. -!- Belongs to peptidase family M17. -!- Formerly EC 3.4.1.1.
|
UniProtKB Entries (1)
| P34629 |
AMPL_CAEEL
Caenorhabditis elegans
Leucine aminopeptidase 1
|
PDB Structure
| PDB | 2HC9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure and Function of Caenorhabditis Elegans Leucine Aminopeptidase
To be Published
|
