CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.25 | Laminin |
|
2.10.25.10 | Laminin |
Domain Context
CATH Clusters
| Superfamily | Laminin |
| Functional Family | Urokinase-type plasminogen activator |
Enzyme Information
| 3.4.21.73 |
U-plasminogen activator.
based on mapping to UniProt P00749
Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.
-!- Formed from the inactive precursor by action of plasmin or plasma kallikrein. -!- Differs in structure from EC 3.4.21.68, and does not bind to fibrin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.21.31 and EC 3.4.99.26.
|
UniProtKB Entries (2)
| Q52L64 |
Q52L64_MOUSE
Mus musculus
ENSMUSG00000076577 protein
|
| Q03405 |
UPAR_HUMAN
Homo sapiens
Urokinase plasminogen activator surface receptor
|
PDB Structure
| PDB | 2FD6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Drosophila |
| Primary Citation |
Structure of human urokinase plasminogen activator in complex with its receptor
Science
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