CATH Domain 2dx1A03

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family

Enzyme Information

UniProtKB Entries (1)

ARHG4_HUMAN

Homo sapiens

Rho guanine nucleotide exchange factor 4

PDB Structure

PDB	2DX1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism Murayama, K., Shirouzu, M., Kawasaki, Y., Kato-Murayama, M., Hanawa-Suetsugu, K., Sakamoto, A., Katsura, Y., Suenaga, A., Toyama, M., Terada, T., Taiji, M., Akiyama, T., Yokoyama, S. J.Biol.Chem.