CATH Domain 2d3cA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.590	Creatine Kinase; Chain A, domain 2
	3.30.590.10	Glutamine synthetase/guanido kinase, catalytic domain

Domain Context

CATH Clusters

Superfamily	Glutamine synthetase/guanido kinase, catalytic domain
Functional Family	Glutamine synthetase

Enzyme Information

6.3.1.2

Glutamine synthetase.

based on mapping to UniProt P38561

ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine.

-!- Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life. -!- Several types have been described, differing in their oligomeric structures and cofactor requirements.

UniProtKB Entries (1)

P38561

GLNA3_MAIZE

Zea mays

Glutamine synthetase root isozyme 3

PDB Structure

PDB	2D3C
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY Unno, H., Uchida, T., Sugawara, H., Kurisu, G., Sugiyama, T., Yamaya, T., Sakakibara, H., Hase, T., Kusunoki, M. J.Biol.Chem.