CATH Domain 2arrA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.497	Antithrombin; Chain I, domain 2
	3.30.497.10	Antithrombin, subunit I, domain 2

Domain Context

CATH Clusters

Superfamily	Antithrombin, subunit I, domain 2
Functional Family	Plasminogen activator inhibitor 2, macrophage

Enzyme Information

UniProtKB Entries (1)

PAI2_HUMAN

Homo sapiens

Plasminogen activator inhibitor 2

PDB Structure

PDB	2ARR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities Di Giusto, D.A., Sutherland, A.P., Jankova, L., Harrop, S.J., Curmi, P.M., King, G.C. J.Mol.Biol.