CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P15273
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P15273
YOPH_YEREN
Yersinia enterocolitica
Tyrosine-protein phosphatase YopH

PDB Structure

PDB 1XXP
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence
Ivanov, M.I., Stuckey, J.A., Schubert, H.L., Saper, M.A., Bliska, J.B.
Mol.Microbiol.
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