CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.20 | Alpha-Beta Barrel | |
3.20.20 | TIM Barrel | |
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
Superfamily | Aldolase class I |
Functional Family | KHG/KDPG aldolase |
Enzyme Information
4.1.3.16 |
4-hydroxy-2-oxoglutarate aldolase.
based on mapping to UniProt P0A955
4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.
-!- The enzymes from rat liver and bovine liver act on both enantiomers of 4-hydroxy-2-oxoglutarate. -!- Formerly EC 4.1.2.1 and EC 4.1.2.31.
|
4.1.2.14 |
2-dehydro-3-deoxy-phosphogluconate aldolase.
based on mapping to UniProt P0A955
2-dehydro-3-deoxy-6-phosphate-D-gluconate = pyruvate + D-glyceraldehyde 3-phosphate.
-!- The enzyme shows no activity with 2-dehydro-3-deoxy-6-phosphate-D- galactonate (cf. EC 4.1.2.55). -!- Also acts on 2-oxobutanoate.
|
UniProtKB Entries (1)
P0A955 |
ALKH_ECOLI
Escherichia coli K-12
KHG/KDPG aldolase
|
PDB Structure
PDB | 1WBH |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Mechanism of the Class I Kdpg Aldolase.
Bioorg.Med.Chem.
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