CATH Domain 1w55A01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.550	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
	3.90.550.10	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family

Enzyme Information

2.7.7.60	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. based on mapping to UniProt Q9PM68 CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol. -!- ATP or UTP can replace CTP, but both are less effective. -!- GTP and TTP are not substrates. -!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.
4.6.1.12	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. based on mapping to UniProt Q9PM68 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl- D-erythritol 2,4-cyclodiphosphate + CMP. -!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

UniProtKB Entries (1)

ISPDF_CAMJE

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Bifunctional enzyme IspD/IspF

PDB Structure

PDB	1W55
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Hexameric Assembly of the Bifunctional Methylerythritol 2,4-Cyclodiphosphate Synthase and Protein-Protein Associations in the Deoxy-Xylulose-Dependent Pathway of Isoprenoid Precursor Biosynthesis Gabrielsen, M., Bond, C.S., Hallyburton, I., Hecht, S., Bacher, A., Eisenreich, W., Rohdich, F., Hunter, W.N. J.Biol.Chem.