CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.19 | Aconitase; domain 4 |
|
3.20.19.10 | Aconitase, domain 4 |
Domain Context
CATH Clusters
| Superfamily | Aconitase, domain 4 |
| Functional Family |
Enzyme Information
| 4.2.1.33 |
3-isopropylmalate dehydratase.
based on mapping to UniProt O59393
(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
-!- Forms part of the leucine-biosynthesis pathway. -!- Brings about the interconversion of the two isomers of isopropylmalate.
|
UniProtKB Entries (1)
| O59393 |
LEUD_PYRHO
Pyrococcus horikoshii OT3
3-isopropylmalate dehydratase small subunit
|
PDB Structure
| PDB | 1V7L |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of the Pyrococcus horikoshii Isopropylmalate Isomerase Small Subunit Provides Insight into the Dual Substrate Specificity of the Enzyme
J.Mol.Biol.
|
