CATH Domain 1ut8A01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.150	DNA polymerase; domain 1
	1.10.150.20	5' to 3' exonuclease, C-terminal subdomain

Domain Context

CATH Clusters

Superfamily	5' to 3' exonuclease, C-terminal subdomain
Functional Family	T5 flap endonuclease

Enzyme Information

3.1.11.3	Exodeoxyribonuclease (lambda-induced). based on mapping to UniProt P06229 Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates. -!- Preference for double-stranded DNA. -!- Does not attack single-strand breaks. -!- Similar enzymes: T4, T5 and T7 exonucleases, mammalian DNase IV. -!- Formerly EC 3.1.4.28.
3.1.11.-	Exodeoxyribonucleases producing 5'-phosphomonoesters. based on mapping to UniProt P06229

UniProtKB Entries (1)

EXO5_BPT5

Escherichia virus T5

T5 flap endonuclease

PDB Structure

PDB	1UT8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Roles of Divalent Metal Ions in Flap Endonuclease-Substrate Interactions Feng, M., Patel, D., Dervan, J., Ceska, T.A., Suck, D., Haq, I., Sayers, J.R. Nat.Struct.Mol.Biol.