CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.8 | Helicase, Ruva Protein; domain 3 |
|
1.10.8.350 | Bacterial muramidase |
Domain Context
CATH Clusters
| Superfamily | Bacterial muramidase |
| Functional Family | Lytic murein transglycosylase B |
Enzyme Information
| 4.2.2.n1 |
Peptidoglycan lytic exotransglycosylase.
based on mapping to UniProt P41052
Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.
|
UniProtKB Entries (1)
| P41052 |
MLTB_ECOLI
Escherichia coli K-12
Membrane-bound lytic murein transglycosylase B
|
PDB Structure
| PDB | 1QDT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Binding of calcium in the EF-hand of Escherichia coli lytic transglycosylase Slt35 is important for stability.
FEBS Lett.
|
