CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Phospholipase A2 group III

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P00630
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P00630
PA2_APIME
Apis mellifera
Phospholipase A2

PDB Structure

PDB 1POC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of bee-venom phospholipase A2 in a complex with a transition-state analogue.
Scott, D.L., Otwinowski, Z., Gelb, M.H., Sigler, P.B.
Science
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