CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.1210 | Cellobiose dehydrogenase, cytochrome domain |
Domain Context
CATH Clusters
| Superfamily | Cellobiose dehydrogenase, cytochrome domain |
| Functional Family |
Enzyme Information
| 1.1.99.18 |
Cellobiose dehydrogenase (acceptor).
based on mapping to UniProt Q01738
Cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor.
-!- Also acts, more slowly, on cello-oligosaccharides, lactose and D-glucosyl-1,4-beta-D-mannose. -!- The enzyme from the white rot fungus Phanerochaete chrysosporium is unusual in having two redoxin domains, one containing a flavin and the other a protoheme group. -!- It transfers reducing equivalents from cellobiose to two types of redox acceptor: two-electron oxidants, including redox dyes, benzoquinones, and molecular oxygen, and one-electron oxidants, including semiquinone species, iron(II) complexes, and the model acceptor cytochrome c. -!- 2,6-dichloroindophenol can act as acceptor in vitro.
|
UniProtKB Entries (1)
| Q01738 |
CDH_PHACH
Phanerochaete chrysosporium
Cellobiose dehydrogenase
|
PDB Structure
| PDB | 1PL3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Phanerochaete |
| Primary Citation |
Biophysical and Structural Analysis of a Novel Heme b Iron Ligation in the Flavocytochrome Cellobiose Dehydrogenase.
J.Biol.Chem.
|
