CATH Classification

Domain Context

CATH Clusters

Superfamily Hypothetical oxidoreductase yiak; domain 3
Functional Family 2,3-diketo-L-gulonate reductase

Enzyme Information

1.1.1.130
3-dehydro-L-gulonate 2-dehydrogenase.
based on mapping to UniProt P37672
3-dehydro-L-gulonate + NAD(P)(+) = (4R,5S)-4,5,6-trihydroxy-2,3- dioxohexanoate + NAD(P)H.

UniProtKB Entries (1)

P37672
DLGD_ECOLI
Escherichia coli K-12
2,3-diketo-L-gulonate reductase

PDB Structure

PDB 1NXU
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK).
Forouhar, F., Lee, I., Benach, J., Kulkarni, K., Xiao, R., Acton, T.B., Montelione, G.T., Tong, L.
J.Biol.Chem.
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