CATH Classification
Level | CATH Code | Description |
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1 | Mainly Alpha |
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1.10 | Orthogonal Bundle |
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1.10.10 | Arc Repressor Mutant, subunit A |
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1.10.10.10 | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
Domain Context
CATH Clusters
Superfamily | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
Functional Family | Caffeic acid 3-O-methyltransferase |
Enzyme Information
2.1.1.68 |
Caffeate O-methyltransferase.
based on mapping to UniProt P28002
S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L- homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
-!- 3,4-dihydroxybenzaldehyde and catechol can act as acceptor, more slowly.
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UniProtKB Entries (1)
P28002 |
COMT1_MEDSA
Medicago sativa
Caffeic acid 3-O-methyltransferase
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PDB Structure
PDB | 1KYW |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structural basis for the modulation of lignin monomer methylation by caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase.
Plant Cell
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