CATH Domain 1k9aB01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.30	SH3 type barrels.
	2.30.30.40	SH3 Domains

Domain Context

CATH Clusters

Superfamily	SH3 Domains
Functional Family

Enzyme Information

2.7.10.2

Non-specific protein-tyrosine kinase.

based on mapping to UniProt P32577

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P32577

CSK_RAT

Rattus norvegicus

Tyrosine-protein kinase CSK

PDB Structure

PDB	1K9A
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Spodoptera
Primary Citation	Structure of the carboxyl-terminal Src kinase, Csk. Ogawa, A., Takayama, Y., Sakai, H., Chong, K.T., Takeuchi, S., Nakagawa, A., Nada, S., Okada, M., Tsukihara, T. J.Biol.Chem.