CATH Domain 1k3fF00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1580	Nucleoside phosphorylase domain

Domain Context

CATH Clusters

Superfamily	Nucleoside phosphorylase domain
Functional Family	Uridine phosphorylase

Enzyme Information

2.4.2.3

Uridine phosphorylase.

based on mapping to UniProt P12758

Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.

-!- The enzyme participates the the pathways of pyrimidine ribonucleosides degradation and salvage. -!- The mammalian enzyme also accepts 2'-deoxyuridine. -!- Formerly EC 2.4.2.23.

UniProtKB Entries (1)

P12758

UDP_ECOLI

Escherichia coli K-12

Uridine phosphorylase

PDB Structure

PDB	1K3F
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Atomic structure at 2.5 A resolution of uridine phosphorylase from E. coli as refined in the monoclinic crystal lattice. Morgunova, E.Yu., Mikhailov, A.M., Popov, A.N., Blagova, E.V., Smirnova, E.A., Vainshtein, B.K., Mao, C., Armstrong, S.R., Ealick, S.E., Komissarov, A.A., Linkova, E.V., Burlakova, A.A., Mironov, A.S., Debabov, V.G. FEBS Lett.