CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.130 | Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 |
|
2.30.130.10 | PUA domain |
Domain Context
CATH Clusters
| Superfamily | PUA domain |
| Functional Family |
Enzyme Information
| 2.4.2.48 |
tRNA-guanine(15) transglycosylase.
based on mapping to UniProt O58843
Guanine(15) in tRNA + 7-cyano-7-carbaguanine = 7-cyano-7-carbaguanine(15) in tRNA + guanine.
-!- Archaeal tRNAs contain the modified nucleoside archaeosine at position 15. -!- This archaeal enzyme catalyzes the exchange of guanine at position 15 of tRNA with the base preQ(0), which is ultimately modified to form the nucleoside archaeosine (cf. EC 2.6.1.97).
|
UniProtKB Entries (1)
| O58843 |
ATGT_PYRHO
Pyrococcus horikoshii OT3
TRNA-guanine(15) transglycosylase
|
PDB Structure
| PDB | 1IQ8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of archaeosine tRNA-guanine transglycosylase.
J.Mol.Biol.
|
