CATH Classification

Domain Context

CATH Clusters

Superfamily L-arginine/glycine Amidinotransferase; Chain A
Functional Family

Enzyme Information

3.5.3.18
Dimethylargininase.
based on mapping to UniProt Q9I4E3
N(omega),N(omega)-dimethyl-L-arginine + H(2)O = dimethylamine + L-citrulline.
-!- Also acts on N(omega)-methyl-L-arginine.

UniProtKB Entries (1)

Q9I4E3
DDAH_PSEAE
Pseudomonas aeruginosa PAO1
N(G),N(G)-dimethylarginine dimethylaminohydrolase

PDB Structure

PDB 1H70
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase.
Murray-Rust, J., Leiper, J., McAlister, M., Phelan, J., Tilley, S., Santa Maria, J., Vallance, P., McDonald, N.
Nat. Struct. Biol.
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