CATH Domain 1gygA02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.60	Lipoxygenase-1
	2.60.60.20	PLAT/LH2 domain

Domain Context

CATH Clusters

Superfamily	PLAT/LH2 domain
Functional Family

Enzyme Information

3.1.4.3

Phospholipase C.

based on mapping to UniProt P0C216

A phosphatidylcholine + H(2)O = 1,2-diacyl-sn-glycerol + phosphocholine.

-!- The bacterial enzyme also acts on sphingomyelin and phosphatidylinositol. -!- The enzyme from seminal plasma does not act on phosphatidylinositol.

UniProtKB Entries (1)

P0C216

PHLC1_CLOPE

Clostridium perfringens str. 13

Phospholipase C

PDB Structure

PDB	1GYG
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of the C. Perfringens Alpha-Toxin with the Active Site Closed by a Flexible Loop Region Eaton, J.T., Naylor, C., Howells, A., Moss, D., Titball, R.W., Basak, A.K. J.Mol.Biol.