CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.25 | UDP-galactose 4-epimerase; domain 1 |
|
3.90.25.10 | UDP-galactose 4-epimerase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | UDP-galactose 4-epimerase, domain 1 |
| Functional Family | GDP-L-fucose synthase 1 |
Enzyme Information
| 1.1.1.271 |
GDP-L-fucose synthase.
based on mapping to UniProt P32055
GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH.
-!- Both human and Escherichia coli enzymes can use NADH in place of NADPH to a slight extent.
|
UniProtKB Entries (1)
| P32055 |
FCL_ECOLI
Escherichia coli K-12
GDP-L-fucose synthase
|
PDB Structure
| PDB | 1GFS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
GDP-fucose synthetase from Escherichia coli: structure of a unique member of the short-chain dehydrogenase/reductase family that catalyzes two distinct reactions at the same active site.
Structure
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