CATH Classification

Domain Context

CATH Clusters

Superfamily Luciferase-like domain
Functional Family

Enzyme Information

1.5.98.2
5,10-methylenetetrahydromethanopterin reductase.
based on mapping to UniProt Q8TXY4
5-methyltetrahydromethanopterin + oxidized coenzyme F420 = 5,10- methylenetetrahydromethanopterin + reduced coenzyme F420.
-!- Catalyzes an intermediate step in methanogenesis from CO(2) and H(2) in archaea. -!- Formerly EC 1.5.99.11.

UniProtKB Entries (1)

Q8TXY4
MER_METKA
Methanopyrus kandleri AV19
5,10-methylenetetrahydromethanopterin reductase

PDB Structure

PDB 1EZW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of coenzyme F(420) dependent methylenetetrahydromethanopterin reductase from two methanogenic archaea.
Shima, S., Warkentin, E., Grabarse, W., Sordel, M., Wicke, M., Thauer, R.K., Ermler, U.
J.Mol.Biol.
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