CATH Domain 1eg9A02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.102	3-layer Sandwich
	2.102.10	Rieske Iron-sulfur Protein
	2.102.10.10	Rieske [2Fe-2S] iron-sulphur domain

Domain Context

CATH Clusters

Superfamily	Rieske [2Fe-2S] iron-sulphur domain
Functional Family	3-phenylpropionate/cinnamic acid dioxygenase subunit alpha

Enzyme Information

1.14.12.12

Naphthalene 1,2-dioxygenase.

based on mapping to UniProt P0A110

Naphthalene + NADH + O(2) = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+).

-!- Comprises a multicomponent system, containing a reductase that is an iron-sulfur flavoprotein (FAD; EC 1.18.1.3), an iron-sulfur oxygenase, and ferredoxin.

UniProtKB Entries (1)

P0A110

NDOB_PSEPU

Pseudomonas putida

Naphthalene 1,2-dioxygenase system, large oxygenase component

PDB Structure

PDB	1EG9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Substrate binding site of naphthalene 1,2-dioxygenase: functional implications of indole binding. Carredano, E., Karlsson, A., Kauppi, B., Choudhury, D., Parales, R.E., Parales, J.V., Lee, K., Gibson, D.T., Eklund, H., Ramaswamy, S. J.Mol.Biol.