CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
Superfamily | NAD(P)-binding Rossmann-like Domain |
Functional Family | Methylenetetrahydrofolate dehydrogenase |
Enzyme Information
1.5.1.15 |
Methylenetetrahydrofolate dehydrogenase (NAD(+)).
based on mapping to UniProt Q02046
5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH.
|
UniProtKB Entries (1)
Q02046 |
MTD1_YEAST
Saccharomyces cerevisiae S288C
Methylenetetrahydrofolate dehydrogenase [NAD(+)]
|
PDB Structure
PDB | 1EDZ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae.
Protein Sci.
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