CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.47 | Peroxisomal Thiolase; Chain A, domain 1 |
|
3.40.47.10 | Thiolase/Chalcone synthase |
Domain Context
CATH Clusters
| Superfamily | 3.40.47.10 |
| Functional Family | Chalcone synthase 2 |
Enzyme Information
| 2.3.1.74 |
Chalcone synthase.
based on mapping to UniProt P30074
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO(2).
-!- The enzyme catalyzes the first committed step in the biosynthesis of flavonoids. -!- It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
|
UniProtKB Entries (1)
| P30074 |
CHS2_MEDSA
Medicago sativa
Chalcone synthase 2
|
PDB Structure
| PDB | 1CML |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis.
Nat.Struct.Biol.
|
