CATH Domain 1ad3A02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.309	Aldehyde Dehydrogenase; Chain A, domain 2
	3.40.309.10	Aldehyde Dehydrogenase; Chain A, domain 2

Domain Context

CATH Clusters

Superfamily	Aldehyde Dehydrogenase; Chain A, domain 2
Functional Family	Aldehyde dehydrogenase

Enzyme Information

1.2.1.5

Aldehyde dehydrogenase (NAD(P)(+)).

based on mapping to UniProt P11883

An aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H.

UniProtKB Entries (1)

AL3A1_RAT

Rattus norvegicus

Aldehyde dehydrogenase, dimeric NADP-preferring

PDB Structure

PDB	1AD3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold. Liu, Z.J., Sun, Y.J., Rose, J., Chung, Y.J., Hsiao, C.D., Chang, W.R., Kuo, I., Perozich, J., Lindahl, R., Hempel, J., Wang, B.C. Nat.Struct.Biol.