The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome c oxidase, subunit VIa
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Cytochrome c oxidase subunit 6A, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Enzyme regulator activity GO:0030234
Binds to and modulates the activity of an enzyme.
9 P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA)
Cytochrome-c oxidase activity GO:0004129
Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
1 Q9W1N3 (/ISS)
Cytochrome-c oxidase activity GO:0004129
Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
1 P10817 (/TAS)
Enzyme regulator activity GO:0030234
Binds to and modulates the activity of an enzyme.
1 Q9W1N3 (/IMP)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aerobic respiration GO:0009060
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
9 P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP)
Mitochondrial respirasome assembly GO:0097250
The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex.
9 P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP) P32799 (/IMP)
Generation of precursor metabolites and energy GO:0006091
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
7 P12074 (/TAS) P12074 (/TAS) P12074 (/TAS) P12074 (/TAS) Q02221 (/TAS) Q02221 (/TAS) Q02221 (/TAS)
Mitochondrial electron transport, cytochrome c to oxygen GO:0006123
The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.
4 P12074 (/TAS) P12074 (/TAS) P12074 (/TAS) P12074 (/TAS)
Mitochondrial electron transport, cytochrome c to oxygen GO:0006123
The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.
1 Q9W1N3 (/IMP)
Mitochondrial electron transport, cytochrome c to oxygen GO:0006123
The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.
1 O74471 (/ISO)
Mitochondrial electron transport, cytochrome c to oxygen GO:0006123
The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.
1 Q9W1N3 (/ISS)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 Q9W1N3 (/IMP)
Aerobic respiration GO:0009060
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
1 Q4QPY7 (/ISS)
Regulation of catalytic activity GO:0050790
Any process that modulates the activity of an enzyme.
1 Q9W1N3 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
17 H6SG15 (/IDA) H6SG15 (/IDA) H6SG15 (/IDA) H6SG15 (/IDA) P12074 (/IDA) P12074 (/IDA) P12074 (/IDA) P12074 (/IDA) P32799 (/IDA) P32799 (/IDA)
(7 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
12 O74471 (/HDA) P32799 (/HDA) P32799 (/HDA) P32799 (/HDA) P32799 (/HDA) P32799 (/HDA) P32799 (/HDA) P32799 (/HDA) P32799 (/HDA) P32799 (/HDA)
(2 more)
Mitochondrial respiratory chain complex IV GO:0005751
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
9 P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA) P32799 (/IDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
4 P12074 (/TAS) P12074 (/TAS) P12074 (/TAS) P12074 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q5ALV9 (/IDA) Q5ALV9 (/IDA)
Respiratory chain complex IV GO:0045277
A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
2 P07471 (/IDA) P07471 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P43024 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q4QPY7 (/ISS)
Mitochondrial respiratory chain complex IV GO:0005751
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
1 Q9W1N3 (/IC)
Mitochondrial respiratory chain complex IV GO:0005751
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
1 O74471 (/ISO)
Mitochondrial respiratory chain complex IV GO:0005751
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
1 Q9W1N3 (/ISS)
Myelin sheath GO:0043209
An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
1 P43024 (/HDA)
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