CATH Superfamily 4.10.410.20
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 4: ectonucleotide pyrophosphatase/phosphodiesterase f...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphodiesterase I activity GO:0004528
Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
|
4 | P15396 (/ISS) P97675 (/ISS) Q5R5M5 (/ISS) Q6DYE8 (/ISS) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
4 | P15396 (/ISS) P97675 (/ISS) Q5R5M5 (/ISS) Q6DYE8 (/ISS) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
4 | P15396 (/ISS) P97675 (/ISS) Q5R5M5 (/ISS) Q6DYE8 (/ISS) |
|
Nucleoside-triphosphate diphosphatase activity GO:0047429
Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide.
|
4 | P15396 (/ISS) P97675 (/ISS) Q5R5M5 (/ISS) Q6DYE8 (/ISS) |
|
Phosphodiesterase I activity GO:0004528
Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
|
1 | O14638 (/IMP) |
|
Phosphodiesterase I activity GO:0004528
Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
|
1 | Q6DYE8 (/ISO) |
|
Phosphodiesterase I activity GO:0004528
Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
|
1 | P97675 (/TAS) |
|
Nucleotide diphosphatase activity GO:0004551
Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides.
|
1 | P97675 (/TAS) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | O14638 (/IDA) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q6DYE8 (/ISO) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | O14638 (/IDA) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q6DYE8 (/ISO) |
|
Nucleoside-triphosphate diphosphatase activity GO:0047429
Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide.
|
1 | O14638 (/IDA) |
|
Nucleoside-triphosphate diphosphatase activity GO:0047429
Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide.
|
1 | Q6DYE8 (/IMP) |
|
Nucleoside-triphosphate diphosphatase activity GO:0047429
Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide.
|
1 | Q6DYE8 (/ISO) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Basophil activation involved in immune response GO:0002276
A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.
|
4 | O14638 (/ISS) P15396 (/ISS) P97675 (/ISS) Q5R5M5 (/ISS) |
|
Pyrimidine nucleotide metabolic process GO:0006220
The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
|
4 | P15396 (/ISS) P97675 (/ISS) Q5R5M5 (/ISS) Q6DYE8 (/ISS) |
|
Negative regulation of mast cell activation involved in immune response GO:0033007
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response.
|
4 | O14638 (/ISS) P15396 (/ISS) P97675 (/ISS) Q5R5M5 (/ISS) |
|
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
|
4 | P15396 (/ISS) P97675 (/ISS) Q5R5M5 (/ISS) Q6DYE8 (/ISS) |
|
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
4 | O14638 (/ISS) P15396 (/ISS) P97675 (/ISS) Q5R5M5 (/ISS) |
|
Negative regulation of mast cell proliferation GO:0070667
Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.
|
4 | O14638 (/ISS) P15396 (/ISS) P97675 (/ISS) Q5R5M5 (/ISS) |
|
Basophil activation involved in immune response GO:0002276
A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.
|
1 | Q6DYE8 (/IMP) |
|
Pyrimidine nucleotide metabolic process GO:0006220
The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
|
1 | O14638 (/IMP) |
|
Pyrimidine nucleotide metabolic process GO:0006220
The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
|
1 | Q6DYE8 (/ISO) |
|
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
|
1 | O14638 (/IDA) |
|
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
|
1 | Q6DYE8 (/ISO) |
|
Nucleoside triphosphate catabolic process GO:0009143
The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
|
1 | O14638 (/IDA) |
|
Nucleoside triphosphate catabolic process GO:0009143
The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
|
1 | Q6DYE8 (/ISO) |
|
Negative regulation of mast cell activation involved in immune response GO:0033007
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response.
|
1 | Q6DYE8 (/IMP) |
|
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | O14638 (/IDA) |
|
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q6DYE8 (/IMP) |
|
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q6DYE8 (/ISO) |
|
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
1 | Q6DYE8 (/IMP) |
|
Regulation of smooth muscle cell differentiation GO:0051150
Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.
|
1 | P97675 (/NAS) |
|
Negative regulation of mast cell proliferation GO:0070667
Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.
|
1 | Q6DYE8 (/IMP) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
4 | P15396 (/ISS) P97675 (/ISS) Q5R5M5 (/ISS) Q6DYE8 (/ISS) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | O14638 (/IDA) Q6DYE8 (/IDA) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
1 | Q6DYE8 (/ISO) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P97675 (/TAS) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | O14638 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q6DYE8 (/ISO) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | O14638 (/HDA) |
