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CATH Superfamily 4.10.410.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Ectonucleotide pyrophosphatase/phosphodiesterase f...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Nucleotide diphosphatase. [EC: 3.6.1.9]
A nucleoside triphosphate + H(2)O = a nucleotide + diphosphate.
  • The enzyme preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates.
  • In vitro the enzyme also acts as a nucleotidohydrolase on ADP, NAD(+), NADP(+), FAD, and CoA.
  • Formerly EC 3.6.1.19.
 8 O14638 P06802 P15396 P22413 P97675 Q5R5M5 Q6DYE8 Q924C3
Phosphodiesterase I. [EC: 3.1.4.1]
Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
  • Hydrolyzes both ribonucleotides and deoxyribonucleotides.
  • Has low activity toward polynucleotides.
  • A 3'-phosphate terminus on the substrate inhibits hydrolysis.
 8 O14638 P06802 P15396 P22413 P97675 Q5R5M5 Q6DYE8 Q924C3
Alkylglycerophosphoethanolamine phosphodiesterase. [EC: 3.1.4.39]
1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol 3-phosphate + ethanolamine.
  • Also acts on acyl and choline analogs.
 4 A1A4K5 Q13822 Q64610 Q9R1E6
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