The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Low-density Lipoprotein Receptor
".
FunFam 176: CG32637-PA protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Neuropeptide receptor activity GO:0008188
Combining with a neuropeptide to initiate a change in cell activity.
|
6 | Q0IGY0 (/ISM) Q5K354 (/ISM) Q5K356 (/ISM) Q5K357 (/ISM) Q5K361 (/ISM) X2JJX6 (/ISM) |
|
Protein-hormone receptor activity GO:0016500
Combining with a protein hormone to initiate a change in cell activity.
|
6 | Q0IGY0 (/ISS) Q5K354 (/ISS) Q5K356 (/ISS) Q5K357 (/ISS) Q5K361 (/ISS) X2JJX6 (/ISS) |
There are 2 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
6 | Q0IGY0 (/ISM) Q5K354 (/ISM) Q5K356 (/ISM) Q5K357 (/ISM) Q5K361 (/ISM) X2JJX6 (/ISM) |
|
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
6 | Q0IGY0 (/ISS) Q5K354 (/ISS) Q5K356 (/ISS) Q5K357 (/ISS) Q5K361 (/ISS) X2JJX6 (/ISS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
6 | Q0IGY0 (/ISM) Q5K354 (/ISM) Q5K356 (/ISM) Q5K357 (/ISM) Q5K361 (/ISM) X2JJX6 (/ISM) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
6 | Q0IGY0 (/ISS) Q5K354 (/ISS) Q5K356 (/ISS) Q5K357 (/ISS) Q5K361 (/ISS) X2JJX6 (/ISS) |
