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CATH Superfamily 4.10.365.10

p27

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
p27
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Cyclin-dependent kinase inhibitor 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004861
Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.
 2 Q9SCR2 (/IGI) Q9SCR2 (/IGI)
Cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004861
Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.
 2 Q9SCR2 (/ISS) Q9SCR2 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 2 Q9SCR2 (/IPI) Q9SCR2 (/IPI)
Kinase inhibitor activity GO:0019210
Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
 2 Q9SCR2 (/IDA) Q9SCR2 (/IDA)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA endoreduplication GO:0042023
Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
 2 Q9SCR2 (/IMP) Q9SCR2 (/IMP)
Negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045736
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
 2 Q9SCR2 (/IDA) Q9SCR2 (/IDA)
Negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045736
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
 2 Q9SCR2 (/ISS) Q9SCR2 (/ISS)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.