The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"p27
".
FunFam 4: Cyclin-dependent kinase inhibitor 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | F4K388 (/IPI) Q8GYJ3 (/IPI) Q8GYJ3 (/IPI) Q9FKB5 (/IPI) Q9FKB5 (/IPI) Q9LRY0 (/IPI) |
|
Cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004861
Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.
|
3 | F4K388 (/IGI) Q8GYJ3 (/IGI) Q8GYJ3 (/IGI) |
|
Cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004861
Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.
|
2 | Q8GYJ3 (/TAS) Q8GYJ3 (/TAS) |
|
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
|
1 | Q9LRY0 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045736
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
|
4 | F4K388 (/IDA) Q8GYJ3 (/IDA) Q8GYJ3 (/IDA) Q9LRY0 (/IDA) |
|
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
|
2 | Q8GYJ3 (/TAS) Q8GYJ3 (/TAS) |
|
Positive regulation of DNA endoreduplication GO:0032877
Any process that activates or increases the frequency, rate or extent of DNA endoreduplication.
|
1 | Q9LRY0 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | F4K388 (/IDA) Q8GYJ3 (/IDA) Q8GYJ3 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q8GYJ3 (/IDA) Q8GYJ3 (/IDA) |