The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc finger, RanBP2-type
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: RNA-binding protein 10 isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
9 A0A023GRW3 (/ISS) A0JMV4 (/ISS) A0JMV4 (/ISS) A4IGK4 (/ISS) Q6DDU9 (/ISS) Q6DDU9 (/ISS) Q6NQZ3 (/ISS) Q8IHG7 (/ISS) Q8IPW6 (/ISS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
4 P98175 (/HDA) P98175 (/HDA) P98175 (/HDA) P98175 (/HDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
4 A0A023GRW3 (/ISS) Q6NQZ3 (/ISS) Q8IHG7 (/ISS) Q8IPW6 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P98175 (/IPI) P98175 (/IPI) P98175 (/IPI) P98175 (/IPI)
MiRNA binding GO:0035198
Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
4 P98175 (/IDA) P98175 (/IDA) P98175 (/IDA) P98175 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
4 P98175 (/IPI) P98175 (/IPI) P98175 (/IPI) P98175 (/IPI)
MiRNA binding GO:0035198
Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
2 P70501 (/ISS) Q99KG3 (/ISS)
MiRNA binding GO:0035198
Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
1 Q99KG3 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q99KG3 (/ISO)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
9 A0A023GRW3 (/ISS) A0JMV4 (/ISS) A0JMV4 (/ISS) A4IGK4 (/ISS) Q6DDU9 (/ISS) Q6DDU9 (/ISS) Q6NQZ3 (/ISS) Q8IHG7 (/ISS) Q8IPW6 (/ISS)
Spliceosomal complex assembly GO:0000245
The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.
5 A0JMV4 (/ISS) A0JMV4 (/ISS) A4IGK4 (/ISS) Q6DDU9 (/ISS) Q6DDU9 (/ISS)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
5 A0JMV4 (/ISS) A0JMV4 (/ISS) A4IGK4 (/ISS) Q6DDU9 (/ISS) Q6DDU9 (/ISS)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 Q99KG3 (/IDA)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q99KG3 (/IDA)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q99KG3 (/IGI)
Regulation of smooth muscle cell apoptotic process GO:0034391
Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process.
1 Q99KG3 (/IGI)
Positive regulation of smooth muscle cell apoptotic process GO:0034393
Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.
1 Q99KG3 (/IDA)
Negative regulation of mRNA splicing, via spliceosome GO:0048025
Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.
1 Q99KG3 (/IMP)
3'-UTR-mediated mRNA stabilization GO:0070935
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
1 Q99KG3 (/IDA)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
11 A0A0S2Z4W4 (/IDA) A0A0S2Z4W4 (/IDA) A0A0S2Z4W4 (/IDA) A0A0S2Z4W4 (/IDA) A0A0S2Z4X1 (/IDA) A0A0S2Z4X1 (/IDA) A0A0S2Z4X1 (/IDA) P98175 (/IDA) P98175 (/IDA) P98175 (/IDA)
(1 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 A0JMV4 (/ISS) A0JMV4 (/ISS) A4IGK4 (/ISS) Q6DDU9 (/ISS) Q6DDU9 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 P98175 (/IDA) P98175 (/IDA) P98175 (/IDA) P98175 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 A0A023GRW3 (/ISS) Q6NQZ3 (/ISS) Q8IHG7 (/ISS) Q8IPW6 (/ISS)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
4 P98175 (/IPI) P98175 (/IPI) P98175 (/IPI) P98175 (/IPI)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q99KG3 (/ISO)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
1 Q99KG3 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q99KG3 (/ISO)