The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DM DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: doublesex- and mab-3-related transcription factor ...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 24 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
7 Q5VZB9 (/ISA) Q8IXT2 (/ISA) Q96MA1 (/ISA) Q96SC8 (/ISA) Q9NQL9 (/ISA) Q9Y5R5 (/ISA) Q9Y5R6 (/ISA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
7 Q5VZB9 (/ISM) Q8IXT2 (/ISM) Q96MA1 (/ISM) Q96SC8 (/ISM) Q9NQL9 (/ISM) Q9Y5R5 (/ISM) Q9Y5R6 (/ISM)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
7 A2A9A2 (/IDA) P23023 (/IDA) P23023 (/IDA) Q8BG36 (/IDA) Q8CFG4 (/IDA) Q8CGW9 (/IDA) Q9QZ59 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
7 A2A9A2 (/IDA) P83758 (/IDA) Q80WT2 (/IDA) Q8BG36 (/IDA) Q8CFG4 (/IDA) Q8CGW9 (/IDA) Q9QZ59 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 A2A9I7 (/IPI) O18214 (/IPI) O18214 (/IPI) P23023 (/IPI) P23023 (/IPI) Q9NQL9 (/IPI)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
4 P23023 (/IDA) P23023 (/IDA) Q8BG36 (/IDA) Q9QZ59 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
4 A0A2R8QDA7 (/IDA) A0SDZ6 (/IDA) B3DKF0 (/IDA) F1R2L1 (/IDA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
4 A0A2R8QDA7 (/IDA) A0SDZ6 (/IDA) B3DKF0 (/IDA) F1R2L1 (/IDA)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
3 Q9VAI8 (/ISS) Q9VDF1 (/ISS) Q9VYE0 (/ISS)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 Q9NQL9 (/NAS) Q9Y5R5 (/NAS) Q9Y5R6 (/NAS)
Proximal promoter sequence-specific DNA binding GO:0000987
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter. The proximal promoter is in cis with and relatively close to the core promoter.
3 B0I1G7 (/IDA) Q3LH63 (/IDA) Q9QZ59 (/IDA)
Proximal promoter sequence-specific DNA binding GO:0000987
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter. The proximal promoter is in cis with and relatively close to the core promoter.
3 C0LZJ1 (/ISS) Q9TT01 (/ISS) Q9Y5R6 (/ISS)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 P23023 (/IDA) P23023 (/IDA) Q9QZ59 (/IDA)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 Q9VAI8 (/ISS) Q9VDF1 (/ISS) Q9VYE0 (/ISS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
3 A2A9A2 (/IPI) Q80WT2 (/IPI) Q9QZ59 (/IPI)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
2 O18214 (/IDA) O18214 (/IDA)
RNA polymerase II regulatory region DNA binding GO:0001012
Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by RNA polymerase II. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 O18214 (/IDA) O18214 (/IDA)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 P23023 (/IDA) P23023 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 F6W2R2 (/IMP) J7FCF0 (/IMP)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
2 P23023 (/IDA) P23023 (/IDA)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q8BG36 (/IC)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 Q9QZ59 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9Y5R6 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9QZ59 (/ISO)

There are 99 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
5 A0A2R8QDA7 (/IMP) A0SDZ6 (/IMP) B3DKF0 (/IMP) F1R2L1 (/IMP) Q9W7K3 (/IMP)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
4 A0A2R8QDA7 (/IMP) A0SDZ6 (/IMP) B3DKF0 (/IMP) F1R2L1 (/IMP)
Male sex determination GO:0030238
The specification of male sex of an individual organism.
4 Q3LH63 (/IMP) Q71MM5 (/IMP) Q8JIR6 (/IMP) Q9QZ59 (/IMP)
Nematode male tail tip morphogenesis GO:0045138
The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome.
4 O18214 (/IGI) O18214 (/IGI) Q9XWN9 (/IGI) Q9XWN9 (/IGI)
Nematode male tail tip morphogenesis GO:0045138
The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome.
4 O18214 (/IMP) O18214 (/IMP) Q9XWN9 (/IMP) Q9XWN9 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
4 O18214 (/IGI) O18214 (/IGI) Q9XWN9 (/IGI) Q9XWN9 (/IGI)
Male sex differentiation GO:0046661
The establishment of the sex of a male organism by physical differentiation.
4 Q3LH63 (/IMP) Q80WT2 (/IMP) Q8JIR6 (/IMP) Q9QZ59 (/IMP)
Muscle fiber development GO:0048747
The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
4 A0A2R8QDA7 (/IMP) A0SDZ6 (/IMP) B3DKF0 (/IMP) F1R2L1 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
3 C0LZJ1 (/ISS) Q9TT01 (/ISS) Q9Y5R6 (/ISS)
Male germ cell proliferation GO:0002176
The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population.
3 C0LZJ1 (/ISS) Q9TT01 (/ISS) Q9Y5R6 (/ISS)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
3 P23023 (/IDA) P23023 (/IDA) Q3LH63 (/IDA)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
3 Q9VAI8 (/ISS) Q9VDF1 (/ISS) Q9VYE0 (/ISS)
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
3 Q3LH63 (/IMP) Q71MM5 (/IMP) Q9QZ59 (/IMP)
Male sex determination GO:0030238
The specification of male sex of an individual organism.
3 C0LZJ1 (/ISS) Q9TT01 (/ISS) Q9Y5R6 (/ISS)
Negative regulation of meiotic nuclear division GO:0045835
Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.
3 C0LZJ1 (/ISS) Q9TT01 (/ISS) Q9Y5R6 (/ISS)
Positive regulation of mitotic nuclear division GO:0045840
Any process that activates or increases the frequency, rate or extent of mitosis.
3 C0LZJ1 (/ISS) Q9TT01 (/ISS) Q9Y5R6 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 Q8BG36 (/IMP) Q9XWN9 (/IMP) Q9XWN9 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 C0LZJ1 (/ISS) Q9TT01 (/ISS) Q9Y5R6 (/ISS)
Male sex differentiation GO:0046661
The establishment of the sex of a male organism by physical differentiation.
3 C0LZJ1 (/ISS) Q9TT01 (/ISS) Q9Y5R6 (/ISS)
Male sex differentiation GO:0046661
The establishment of the sex of a male organism by physical differentiation.
3 P23023 (/TAS) P23023 (/TAS) Q925A6 (/TAS)
Sertoli cell differentiation GO:0060008
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
3 C0LZJ1 (/ISS) Q9TT01 (/ISS) Q9Y5R6 (/ISS)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 O18214 (/IC) O18214 (/IC)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 B0I1G7 (/IDA) Q9QZ59 (/IDA)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 O18214 (/IMP) O18214 (/IMP)
Male germ cell proliferation GO:0002176
The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population.
2 Q71MM5 (/IMP) Q9QZ59 (/IMP)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 P23023 (/IMP) P23023 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
2 Q9QZ59 (/IMP) Q9VYE0 (/IMP)
Imaginal disc-derived male genitalia development GO:0007485
The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.
2 P23023 (/IGI) P23023 (/IGI)
Imaginal disc-derived female genitalia development GO:0007486
The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.
2 P23023 (/IGI) P23023 (/IGI)
Imaginal disc-derived female genitalia development GO:0007486
The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.
2 P23023 (/IMP) P23023 (/IMP)
Sex determination GO:0007530
Any process that establishes and transmits the specification of sexual status of an individual organism.
2 P23023 (/TAS) P23023 (/TAS)
Sex differentiation GO:0007548
The establishment of the sex of an organism by physical differentiation.
2 O18214 (/IMP) O18214 (/IMP)
Courtship behavior GO:0007619
The behavioral interactions between organisms for the purpose of attracting sexual partners.
2 P23023 (/NAS) P23023 (/NAS)
Male courtship behavior GO:0008049
The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster.
2 P23023 (/TAS) P23023 (/TAS)
Adult locomotory behavior GO:0008344
Locomotory behavior in a fully developed and mature organism.
2 F6W2R2 (/IMP) J7FCF0 (/IMP)
Axon midline choice point recognition GO:0016199
The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.
2 P23023 (/IMP) P23023 (/IMP)
Somatic sex determination GO:0018993
The determination of sex and sexual phenotypes in an organism's soma.
2 P23023 (/TAS) P23023 (/TAS)
Female somatic sex determination GO:0019101
The determination of sex and sexual phenotypes in a female organism's soma.
2 P23023 (/TAS) P23023 (/TAS)
Transmission of nerve impulse GO:0019226
The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission.
2 F6W2R2 (/ISS) J7FCF0 (/ISS)
Ventral spinal cord interneuron specification GO:0021521
The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.
2 F6W2R2 (/ISS) J7FCF0 (/ISS)
Genital disc development GO:0035215
Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia.
2 P23023 (/IMP) P23023 (/IMP)
Male courtship behavior, veined wing generated song production GO:0045433
The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.
2 P23023 (/TAS) P23023 (/TAS)
Male analia development GO:0045496
The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.
2 P23023 (/NAS) P23023 (/NAS)
Female analia development GO:0045497
The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.
2 P23023 (/NAS) P23023 (/NAS)
Sex comb development GO:0045498
The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg.
2 P23023 (/TAS) P23023 (/TAS)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 P23023 (/NAS) P23023 (/NAS)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 P23023 (/NAS) P23023 (/NAS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 P23023 (/TAS) P23023 (/TAS)
Female sex differentiation GO:0046660
The establishment of the sex of a female organism by physical differentiation.
2 P23023 (/TAS) P23023 (/TAS)
Sex-specific pigmentation GO:0048071
Establishment of a pattern of pigment in one sex that is not observed in the other sex.
2 P23023 (/TAS) P23023 (/TAS)
Negative regulation of developmental pigmentation GO:0048086
Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
2 P23023 (/TAS) P23023 (/TAS)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
1 Q9QZ59 (/IMP)
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
1 Q8CFG4 (/IMP)
Positive regulation of neuroblast proliferation GO:0002052
Any process that activates or increases the rate of neuroblast proliferation.
1 A2A9A2 (/IMP)
Developmental process involved in reproduction GO:0003006
A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring.
1 Q9QZ59 (/IGI)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 Q9W7K3 (/IDA)
Male meiosis I GO:0007141
A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
1 Q8CGW9 (/IMP)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
1 Q71MM5 (/IMP)
Spermatid nucleus elongation GO:0007290
The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation.
1 Q8CGW9 (/IMP)
Sex differentiation GO:0007548
The establishment of the sex of an organism by physical differentiation.
1 Q9NQL9 (/NAS)
Adult walking behavior GO:0007628
The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
1 Q80WT2 (/IMP)
Germ cell migration GO:0008354
The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
1 Q9QZ59 (/IMP)
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
1 Q3LH63 (/IEP)
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
1 P85119 (/ISS)
Female gonad development GO:0008585
The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
1 B0I1G7 (/IMP)
Regulation of somitogenesis GO:0014807
Any process that modulates the frequency, rate or extent of somitogenesis.
1 Q8BG36 (/IGI)
Regulation of somitogenesis GO:0014807
Any process that modulates the frequency, rate or extent of somitogenesis.
1 Q8BG36 (/IMP)
Transmission of nerve impulse GO:0019226
The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission.
1 Q80WT2 (/IMP)
Ventral spinal cord interneuron specification GO:0021521
The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.
1 Q80WT2 (/IMP)
Telencephalon development GO:0021537
The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.
1 Q5UU75 (/IMP)
Cerebral cortex regionalization GO:0021796
The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops.
1 A2A9A2 (/IMP)
Neurogenesis GO:0022008
Generation of cells within the nervous system.
1 Q2MJB4 (/IMP)
Female sex determination GO:0030237
The specification of female sex of an individual organism.
1 B0I1G7 (/IMP)
Male sex determination GO:0030238
The specification of male sex of an individual organism.
1 Q9PTQ7 (/TAS)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
1 Q925A6 (/IDA)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
1 Q9QZ59 (/ISO)
Skeletal muscle cell differentiation GO:0035914
The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.
1 A2A9A2 (/IMP)
Regulation of odontogenesis of dentin-containing tooth GO:0042487
Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.
1 Q80WT2 (/IMP)
Negative regulation of meiotic nuclear division GO:0045835
Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.
1 Q9QZ59 (/IMP)
Positive regulation of mitotic nuclear division GO:0045840
Any process that activates or increases the frequency, rate or extent of mitosis.
1 Q9QZ59 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q3LH63 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P85119 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q9QZ59 (/IDA)
Female sex differentiation GO:0046660
The establishment of the sex of a female organism by physical differentiation.
1 B0I1G7 (/IMP)
Oocyte development GO:0048599
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
1 Q9QZ59 (/IMP)
Neuron fate specification GO:0048665
The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
1 A2A9A2 (/IMP)
Embryonic skeletal system development GO:0048706
The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.
1 Q8BG36 (/IMP)
Sertoli cell differentiation GO:0060008
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
1 Q9QZ59 (/IMP)
Sertoli cell development GO:0060009
The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.
1 Q9QZ59 (/IMP)
Corticotropin hormone secreting cell differentiation GO:0060128
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.
1 Q5UU75 (/IMP)
Male mating behavior GO:0060179
The specific behavior of a male organism that is associated with reproduction.
1 Q8CFG4 (/IMP)
Positive regulation of meiosis I GO:0060903
Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
1 Q9QZ59 (/IMP)
Dopaminergic neuron differentiation GO:0071542
The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.
1 A2A9A2 (/IMP)
Seminiferous tubule development GO:0072520
The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.
1 Q9PTQ7 (/NAS)
Regulation of nodal signaling pathway GO:1900107
Any process that modulates the frequency, rate or extent of nodal signaling pathway.
1 Q9QZ59 (/IMP)
Positive regulation of histone H3-K9 dimethylation GO:1900111
Any process that activates or increases the frequency, rate or extent of histone H3-K9 dimethylation.
1 Q8CGW9 (/IMP)
Positive regulation of histone H3-K9 trimethylation GO:1900114
Any process that activates or increases the frequency, rate or extent of histone H3-K9 trimethylation.
1 Q8CGW9 (/IMP)
Positive regulation of male gonad development GO:2000020
Any process that activates or increases the frequency, rate or extent of male gonad development.
1 Q9QZ59 (/IMP)
Positive regulation of myotome development GO:2000287
Any process that activates or increases the frequency, rate or extent of myotome development.
1 Q8BG36 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 A2A9A2 (/IDA) Q80WT2 (/IDA) Q9QZ59 (/IDA) Q9W7K3 (/IDA) Q9Y5R6 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 O18214 (/IC) O18214 (/IC) P23023 (/IC) P23023 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 C0LZJ1 (/ISS) Q9TT01 (/ISS) Q9Y5R6 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 F6W2R2 (/IMP) J7FCF0 (/IMP)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8BG36 (/ISO) Q9QZ59 (/ISO)
XY body GO:0001741
A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.
1 Q8CGW9 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9QZ59 (/IDA)