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CATH Superfamily 3.90.870.20

Carbamoyltransferase, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Carbamoyltransferase, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Decarbamoylnovobiocin carbamoyltransferase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Nebramycin 5' synthase. [EC: 6.1.2.2]
(1) Tobramycin + carbamoyl phosphate + ATP + H(2)O = nebramycin 5' + AMP + diphosphate + phosphate. (2) Kanamycin A + carbamoyl phosphate + ATP + H(2)O = 6''-O- carbamoylkanamycin A + AMP + diphosphate + phosphate.
  • The enzyme from the bacterium Streptoalloteichus tenebrarius catalyzes the activation of carbamoyl phosphate to O-carbamoyladenylate and the subsequent carbamoylation of kanamycin and tobramycin.
  • Formerly EC 2.1.3.13 and EC 2.1.3.14.
 1 Q70IY1
Decarbamoylnovobiocin carbamoyltransferase. [EC: 2.1.3.12]
Carbamoyl phosphate + decarbamoylnovobiocin = phosphate + novobiocin.
  • The enzyme catalyzes the last step in the biosynthesis of the aminocoumarin antibiotic novobiocin.
  • The reaction is activated by ATP.
 1 Q9L9F4