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CATH Superfamily 3.90.870.10

DHBP synthase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DHBP synthase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Riboflavin biosynthesis protein RibBA

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3,4-dihydroxy-2-butanone-4-phosphate synthase. [EC: 4.1.99.12]
D-ribulose 5-phosphate = formate + L-3,4-dihydroxybutan-2-one 4-phosphate.
  • The reaction involves an intramolecular skeletal rearrangement, with the bonds in D-ribulose 5-phosphate that connect C-3 and C-5 to C-4 being broken, C-4 being removed as formate and reconnection of C-3 and C-5.
  • The phosphorylated four-carbon product (L-3,4-dihydroxybutan-2-one 4-phosphate) is an intermediate in the biosynthesis of riboflavin.
 1193 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051
(1183 more...)
GTP cyclohydrolase II. [EC: 3.5.4.25]
GTP + 3 H(2)O = formate + 2,5-diamino-6-hydroxy-4-(5-phospho-D- ribosylamino)pyrimidine + diphosphate.
  • Two C-N bonds are hydrolyzed, releasing formate, with simultaneous removal of the terminal diphosphate.
 1075 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051 A0A045J051
(1065 more...)