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CATH Superfamily 3.90.810.10

CRIB domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CRIB domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: CDC42 small effector protein 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 16 Q9NRR3 (/IPI) Q9NRR3 (/IPI) Q9NRR3 (/IPI) Q9NRR3 (/IPI) Q9NRR3 (/IPI) Q9NRR3 (/IPI) Q9NRR3 (/IPI) Q9NRR3 (/IPI) Q9NRR3 (/IPI) Q9NRR3 (/IPI)
(6 more)
Signaling adaptor activity GO:0035591
The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.
 16 Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA)
(6 more)
Signaling adaptor activity GO:0035591
The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.
 16 Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO)
(6 more)
Rho GTPase binding GO:0017048
Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.
 6 Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of signal transduction GO:0009966
Any process that modulates the frequency, rate or extent of signal transduction.
 36 A1L1K4 (/ISS) A9JR56 (/ISS) Q28EW5 (/ISS) Q28GG3 (/ISS) Q28GG3 (/ISS) Q28GG3 (/ISS) Q4V853 (/ISS) Q4V853 (/ISS) Q5FVD7 (/ISS) Q5FVD7 (/ISS)
(26 more)
Regulation of signal transduction GO:0009966
Any process that modulates the frequency, rate or extent of signal transduction.
 16 Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA)
(6 more)
Regulation of signal transduction GO:0009966
Any process that modulates the frequency, rate or extent of signal transduction.
 16 Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO)
(6 more)
Regulation of Rho protein signal transduction GO:0035023
Any process that modulates the frequency, rate or extent of Rho protein signal transduction.
 6 Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 36 A1L1K4 (/ISS) A9JR56 (/ISS) Q28EW5 (/ISS) Q28GG3 (/ISS) Q28GG3 (/ISS) Q28GG3 (/ISS) Q4V853 (/ISS) Q4V853 (/ISS) Q5FVD7 (/ISS) Q5FVD7 (/ISS)
(26 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 16 Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA) Q9NRR3 (/IDA)
(6 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 16 Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO) Q8BGH7 (/ISO)
(6 more)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
 6 Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS) Q9VNE7 (/ISS)
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