The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"CRIB domain
".
FunFam 20: WASP (Actin cytoskeleton modulator) homolog
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q17795 (/IPI) Q8MQE6 (/IPI) |
|
Cytoskeletal regulatory protein binding GO:0005519
Interacting selectively and non-covalently with any protein involved in modulating the reorganization of the cytoskeleton.
|
1 | Q8MQE6 (/IPI) |
|
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
|
1 | Q8MQE6 (/IPI) |
|
GTPase binding GO:0051020
Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q8MQE6 (/IPI) |
|
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
1 | Q8MQE6 (/IC) |
There are 12 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Epithelial cell migration GO:0010631
The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.
|
2 | Q17795 (/IMP) Q8MQE6 (/IMP) |
|
Morphogenesis of embryonic epithelium GO:0016331
The process in which the anatomical structures of embryonic epithelia are generated and organized.
|
2 | Q17795 (/IMP) Q8MQE6 (/IMP) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
2 | Q17795 (/IMP) Q8MQE6 (/IMP) |
|
Regulation of Arp2/3 complex-mediated actin nucleation GO:0034315
Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
|
2 | Q17795 (/IDA) Q8MQE6 (/IDA) |
|
Microvillus organization GO:0032528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.
|
1 | Q8MQE6 (/IGI) |
|
Microvillus organization GO:0032528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.
|
1 | Q8MQE6 (/IMP) |
|
Embryonic ectodermal digestive tract morphogenesis GO:0048613
The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.
|
1 | Q8MQE6 (/IGI) |
|
Embryonic ectodermal digestive tract morphogenesis GO:0048613
The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.
|
1 | Q8MQE6 (/IMP) |
|
Positive regulation of oviposition GO:1901046
Any process that activates or increases the frequency, rate or extent of oviposition.
|
1 | Q8MQE6 (/IGI) |
|
Positive regulation of oviposition GO:1901046
Any process that activates or increases the frequency, rate or extent of oviposition.
|
1 | Q8MQE6 (/IMP) |
|
Positive regulation of clathrin-dependent endocytosis GO:2000370
Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.
|
1 | Q8MQE6 (/IGI) |
|
Positive regulation of clathrin-dependent endocytosis GO:2000370
Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.
|
1 | Q8MQE6 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
|
2 | Q17795 (/IDA) Q8MQE6 (/IDA) |
|
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
|
2 | Q17795 (/IDA) Q8MQE6 (/IDA) |
|
Presynaptic periactive zone GO:0036062
A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development.
|
1 | Q8MQE6 (/IDA) |
