The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"CRIB domain
".
FunFam 12: Non-specific serine/threonine protein kinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
1 | P50527 (/IDA) |
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
1 | P50527 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P50527 (/IPI) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cdc42 protein signal transduction GO:0032488
A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state.
|
1 | P50527 (/IGI) |
|
Positive regulation of establishment of bipolar cell polarity regulating cell shape GO:0061161
Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.
|
1 | P50527 (/IGI) |
|
Positive regulation of pheromone response MAPK cascade GO:0062038
Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade.
|
1 | P50527 (/IMP) |
|
Regulation of microtubule cytoskeleton organization GO:0070507
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
|
1 | P50527 (/IGI) |
|
Negative regulation of mitotic actomyosin contractile ring contraction GO:1903472
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction.
|
1 | P50527 (/IMP) |
|
Positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape GO:2000247
Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.
|
1 | P50527 (/IMP) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Actomyosin contractile ring GO:0005826
A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis.
|
1 | P50527 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P50527 (/HDA) |
|
Spindle microtubule GO:0005876
Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
|
1 | P50527 (/IDA) |
|
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | P50527 (/HDA) |
|
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | P50527 (/IDA) |
|
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
|
1 | P50527 (/HDA) |
|
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
|
1 | P50527 (/IDA) |
|
Cdc42 GTPase complex GO:0071521
A protein complex formed by the association of the small GTPase Cdc42 with additional proteins. In Schizosaccharomyces the complex contains the Cdc42, Ras1, Scd1, Scd2, andShk1 proteins, and functions in the Ras1-Scd GTPase signalling pathway.
|
1 | P50527 (/IPI) |
|
Actomyosin contractile ring, intermediate layer GO:0120105
The region of the actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer.
|
1 | P50527 (/IDA) |
