The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleoside Triphosphate Pyrophosphohydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 53: Coenzyme A diphosphatase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity GO:0008413
Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate = 8-oxo-7,8-dihydroguanosine phosphate + diphosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription.
6 Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA)
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity GO:0008413
Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate = 8-oxo-7,8-dihydroguanosine phosphate + diphosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription.
6 Q12524 (/IMP) Q12524 (/IMP) Q12524 (/IMP) Q12524 (/IMP) Q12524 (/IMP) Q12524 (/IMP)
Pyrophosphatase activity GO:0016462
Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
6 Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
6 Q12524 (/IMP) Q12524 (/IMP) Q12524 (/IMP) Q12524 (/IMP) Q12524 (/IMP) Q12524 (/IMP)
Coenzyme A metabolic process GO:0015936
The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
6 Q12524 (/IC) Q12524 (/IC) Q12524 (/IC) Q12524 (/IC) Q12524 (/IC) Q12524 (/IC)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
6 Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA) Q12524 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 Q12524 (/HDA) Q12524 (/HDA) Q12524 (/HDA) Q12524 (/HDA) Q12524 (/HDA) Q12524 (/HDA)
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