The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleoside Triphosphate Pyrophosphohydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: diphosphoinositol polyphosphate phosphohydrolase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Diphosphoinositol-polyphosphate diphosphatase activity GO:0008486
Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate.
29 O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA)
(19 more)
Diphosphoinositol-polyphosphate diphosphatase activity GO:0008486
Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate.
25 A2VE79 (/ISS) P0C028 (/ISS) P0C028 (/ISS) P0C028 (/ISS) Q566C7 (/ISS) Q8NFP7 (/ISS) Q8NFP7 (/ISS) Q8NFP7 (/ISS) Q8NFP7 (/ISS) Q8R2U6 (/ISS)
(15 more)
Diphosphoinositol-polyphosphate diphosphatase activity GO:0008486
Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate.
20 O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS)
(10 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
14 O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA)
(4 more)
SnoRNA binding GO:0030515
Interacting selectively and non-covalently with small nucleolar RNA.
13 Q5RAF0 (/ISS) Q5RAF0 (/ISS) Q5RAF0 (/ISS) Q5RAF0 (/ISS) Q5RAF0 (/ISS) Q5RAF0 (/ISS) Q99MY2 (/ISS) Q9NZJ9 (/ISS) Q9NZJ9 (/ISS) Q9NZJ9 (/ISS)
(3 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 Q8NFP7 (/IPI) Q8NFP7 (/IPI) Q8NFP7 (/IPI) Q8NFP7 (/IPI) Q9NZJ9 (/IPI) Q9NZJ9 (/IPI) Q9NZJ9 (/IPI) Q9NZJ9 (/IPI) Q9NZJ9 (/IPI) Q9NZJ9 (/IPI)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
3 A2VE79 (/ISS) Q566C7 (/ISS) Q9JI46 (/ISS)
Diphosphoinositol-polyphosphate diphosphatase activity GO:0008486
Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate.
3 Q8R2U6 (/ISO) Q8R2U6 (/ISO) Q9JI46 (/ISO)
SnoRNA binding GO:0030515
Interacting selectively and non-covalently with small nucleolar RNA.
2 Q8R2U6 (/IDA) Q8R2U6 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q9JI46 (/ISO)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Inositol phosphate metabolic process GO:0043647
The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
36 O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS)
(26 more)
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
14 O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS)
(4 more)
Diadenosine polyphosphate catabolic process GO:0015961
The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.
14 O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS)
(4 more)
Diphosphoinositol polyphosphate catabolic process GO:0071544
The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.
14 O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA) O95989 (/IDA)
(4 more)
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
6 Q9NZJ9 (/TAS) Q9NZJ9 (/TAS) Q9NZJ9 (/TAS) Q9NZJ9 (/TAS) Q9NZJ9 (/TAS) Q9NZJ9 (/TAS)
Cyclic-nucleotide-mediated signaling GO:0019935
Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell.
6 Q9NZJ9 (/TAS) Q9NZJ9 (/TAS) Q9NZJ9 (/TAS) Q9NZJ9 (/TAS) Q9NZJ9 (/TAS) Q9NZJ9 (/TAS)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
6 Q9NZJ9 (/NAS) Q9NZJ9 (/NAS) Q9NZJ9 (/NAS) Q9NZJ9 (/NAS) Q9NZJ9 (/NAS) Q9NZJ9 (/NAS)
Nucleotide metabolic process GO:0009117
The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
3 Q7JVG2 (/IDA) Q7JVG2 (/IDA) Q7JVG2 (/IDA)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
3 Q7JVG2 (/IMP) Q7JVG2 (/IMP) Q7JVG2 (/IMP)
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
3 Q7JVG2 (/IMP) Q7JVG2 (/IMP) Q7JVG2 (/IMP)
Inositol phosphate metabolic process GO:0043647
The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
3 Q7JVG2 (/IDA) Q7JVG2 (/IDA) Q7JVG2 (/IDA)
Lipid homeostasis GO:0055088
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
3 Q7JVG2 (/IMP) Q7JVG2 (/IMP) Q7JVG2 (/IMP)
Diphosphoinositol polyphosphate catabolic process GO:0071544
The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.
3 A2VE79 (/ISS) Q566C7 (/ISS) Q9JI46 (/ISS)
Phosphatidylinositol metabolic process GO:0046488
The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
1 Q99MY2 (/NAS)
Diphosphoinositol polyphosphate catabolic process GO:0071544
The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.
1 Q9JI46 (/ISO)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
46 A0A024RBD0 (/IDA) A0A024RBD0 (/IDA) A0A024RBD0 (/IDA) A0A024RBD0 (/IDA) A0A024RBD0 (/IDA) A0A024RBD0 (/IDA) A0A024RBG1 (/IDA) A0A024RBG1 (/IDA) A0A024RBG1 (/IDA) A0A024RBG1 (/IDA)
(36 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
36 O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS) O95989 (/TAS)
(26 more)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
12 Q96G61 (/IDA) Q96G61 (/IDA) Q96G61 (/IDA) Q96G61 (/IDA) Q96G61 (/IDA) Q96G61 (/IDA) Q96G61 (/IDA) Q96G61 (/IDA) Q96G61 (/IDA) Q96G61 (/IDA)
(2 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 P0C027 (/ISO) P0C027 (/ISO) P0C027 (/ISO) P0C028 (/ISO) P0C028 (/ISO) P0C028 (/ISO) Q8R2U6 (/ISO) Q8R2U6 (/ISO) Q9JI46 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q7JVG2 (/IDA) Q7JVG2 (/IDA) Q7JVG2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q7JVG2 (/IDA) Q7JVG2 (/IDA) Q7JVG2 (/IDA)
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