The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
5'-Nucleotidase, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Bifunctional 2',3'-cyclic-nucleotide 2'-phosphodie...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3'-nucleotidase activity GO:0008254
Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate.
8 P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA)
3'-nucleotidase activity GO:0008254
Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate.
8 P08331 (/RCA) P08331 (/RCA) P08331 (/RCA) P08331 (/RCA) P08331 (/RCA) P08331 (/RCA) P08331 (/RCA) P08331 (/RCA)
2',3'-cyclic-nucleotide 2'-phosphodiesterase activity GO:0008663
Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.
8 P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA)
2',3'-cyclic-nucleotide 2'-phosphodiesterase activity GO:0008663
Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.
8 P08331 (/RCA) P08331 (/RCA) P08331 (/RCA) P08331 (/RCA) P08331 (/RCA) P08331 (/RCA) P08331 (/RCA) P08331 (/RCA)
2',3'-cyclic-nucleotide 2'-phosphodiesterase activity GO:0008663
Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.
3 Q8EBF3 (/ISS) Q9KP17 (/ISS) Q9KP17 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
8 P08331 (/IEP) P08331 (/IEP) P08331 (/IEP) P08331 (/IEP) P08331 (/IEP) P08331 (/IEP) P08331 (/IEP) P08331 (/IEP)
Nucleotide catabolic process GO:0009166
The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
8 P08331 (/IEP) P08331 (/IEP) P08331 (/IEP) P08331 (/IEP) P08331 (/IEP) P08331 (/IEP) P08331 (/IEP) P08331 (/IEP)
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
3 Q8EBF3 (/ISS) Q9KP17 (/ISS) Q9KP17 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Outer membrane-bounded periplasmic space GO:0030288
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
8 P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA)
Periplasmic space GO:0042597
The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
8 P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA) P08331 (/IDA)
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