CATH Superfamily 3.90.70.80
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: OTU domain-containing protein 5 isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
6 | Q08BW0 (/ISS) Q2YDU3 (/ISS) Q3U2S4 (/ISS) Q640H3 (/ISS) Q6GL44 (/ISS) Q7ZX21 (/ISS) |
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
2 | Q96G74 (/IDA) Q96G74 (/IDA) |
|
Lys63-specific deubiquitinase activity GO:0061578
Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein.
|
2 | Q96G74 (/EXP) Q96G74 (/EXP) |
|
Lys63-specific deubiquitinase activity GO:0061578
Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein.
|
2 | Q96G74 (/IDA) Q96G74 (/IDA) |
|
Ubiquitinyl hydrolase activity GO:0101005
Catalysis of the hydrolysis of ubiquitin from proteins and other molecules.
|
2 | Q96G74 (/IDA) Q96G74 (/IDA) |
|
Lys48-specific deubiquitinase activity GO:1990380
Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein.
|
2 | Q96G74 (/IDA) Q96G74 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q3U2S4 (/IPI) |
|
Lys63-specific deubiquitinase activity GO:0061578
Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein.
|
1 | Q3U2S4 (/ISO) |
|
Ubiquitinyl hydrolase activity GO:0101005
Catalysis of the hydrolysis of ubiquitin from proteins and other molecules.
|
1 | Q3U2S4 (/ISO) |
|
Lys48-specific deubiquitinase activity GO:1990380
Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein.
|
1 | Q3U2S4 (/ISO) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
6 | Q08BW0 (/ISS) Q2YDU3 (/ISS) Q3U2S4 (/ISS) Q640H3 (/ISS) Q6GL44 (/ISS) Q7ZX21 (/ISS) |
|
Protein K63-linked deubiquitination GO:0070536
A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.
|
6 | Q08BW0 (/ISS) Q2YDU3 (/ISS) Q3U2S4 (/ISS) Q640H3 (/ISS) Q6GL44 (/ISS) Q7ZX21 (/ISS) |
|
Protein K48-linked deubiquitination GO:0071108
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
|
6 | Q08BW0 (/ISS) Q2YDU3 (/ISS) Q3U2S4 (/ISS) Q640H3 (/ISS) Q6GL44 (/ISS) Q7ZX21 (/ISS) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
2 | Q96G74 (/IDA) Q96G74 (/IDA) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
2 | Q96G74 (/TAS) Q96G74 (/TAS) |
|
Negative regulation of type I interferon production GO:0032480
Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
2 | Q96G74 (/TAS) Q96G74 (/TAS) |
|
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
2 | Q96G74 (/IDA) Q96G74 (/IDA) |
|
Protein K63-linked deubiquitination GO:0070536
A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.
|
2 | Q96G74 (/IDA) Q96G74 (/IDA) |
|
Protein K48-linked deubiquitination GO:0071108
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
|
2 | Q96G74 (/IDA) Q96G74 (/IDA) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
1 | Q3U2S4 (/ISO) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
1 | Q3U2S4 (/IMP) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
1 | Q3U2S4 (/IDA) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
1 | Q3U2S4 (/IMP) |
|
CD8-positive, alpha-beta T cell differentiation GO:0043374
The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell.
|
1 | Q3U2S4 (/IMP) |
|
T-helper 17 cell lineage commitment GO:0072540
The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.
|
1 | Q3U2S4 (/IMP) |
|
Interleukin-9 secretion GO:0072607
The regulated release of interleukin-9 from a cell.
|
1 | Q3U2S4 (/IMP) |
|
Interleukin-21 secretion GO:0072619
The regulated release of interleukin-21 from a cell.
|
1 | Q3U2S4 (/IMP) |
|
Negative regulation of interleukin-17 secretion GO:1905077
Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17 secretion.
|
1 | Q3U2S4 (/IGI) |
|
Negative regulation of interleukin-17 secretion GO:1905077
Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17 secretion.
|
1 | Q3U2S4 (/IMP) |
|
Regulation of T-helper 17 type immune response GO:2000316
Any process that modulates the frequency, rate or extent of T-helper 17 type immune response.
|
1 | Q3U2S4 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q96G74 (/TAS) Q96G74 (/TAS) |