The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Plus-3 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Related to Pol II transcription elongation factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
4 P53064 (/IDA) P53064 (/IDA) P53064 (/IDA) P53064 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P53064 (/IPI) P53064 (/IPI) P53064 (/IPI) P53064 (/IPI)
RNA polymerase II C-terminal domain phosphoserine binding GO:1990269
Interacting selectively and non-covalently with phosphorylated serine residues in the C-terminal domain of RNA polymerase II.
4 P53064 (/IDA) P53064 (/IDA) P53064 (/IDA) P53064 (/IDA)

There are 27 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
SnoRNA transcription by RNA polymerase II GO:0001015
The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
DNA-templated transcription, termination GO:0006353
The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
4 P53064 (/IGI) P53064 (/IGI) P53064 (/IGI) P53064 (/IGI)
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
4 P53064 (/IGI) P53064 (/IGI) P53064 (/IGI) P53064 (/IGI)
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
SnoRNA 3'-end processing GO:0031126
Any process involved in forming the mature 3' end of a snoRNA molecule.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Regulation of chromatin silencing at telomere GO:0031938
Any process that affects the rate, extent or location of chromatin silencing at telomeres.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex GO:0034402
The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Regulation of histone H3-K4 methylation GO:0051569
Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Global genome nucleotide-excision repair GO:0070911
The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Regulation of transcription-coupled nucleotide-excision repair GO:0090262
Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
4 P53064 (/IGI) P53064 (/IGI) P53064 (/IGI) P53064 (/IGI)
Regulation of histone H3-K79 methylation GO:2001160
Any process that modulates the frequency, rate or extent of histone H3-K79 methylation.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues GO:2001163
Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues GO:2001165
Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Regulation of histone H2B ubiquitination GO:2001166
Any process that modulates the frequency, rate or extent of histone H2B ubiquitination.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Regulation of histone H2B conserved C-terminal lysine ubiquitination GO:2001173
Any process that modulates the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.
4 P53064 (/IDA) P53064 (/IDA) P53064 (/IDA) P53064 (/IDA)
Regulation of histone H2B conserved C-terminal lysine ubiquitination GO:2001173
Any process that modulates the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.
4 P53064 (/IMP) P53064 (/IMP) P53064 (/IMP) P53064 (/IMP)
Positive regulation of transcription elongation from RNA polymerase I promoter GO:2001209
Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.
4 P53064 (/IDA) P53064 (/IDA) P53064 (/IDA) P53064 (/IDA)
Regulation of sterigmatocystin biosynthetic process GO:0010913
Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
2 Q5B4G0 (/IMP) Q5B4G0 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
2 Q5B4G0 (/IMP) Q5B4G0 (/IMP)
Sexual sporulation resulting in formation of a cellular spore GO:0043935
The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
2 Q5B4G0 (/IMP) Q5B4G0 (/IMP)
Asexual sporulation resulting in formation of a cellular spore GO:0043936
The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
2 Q5B4G0 (/IMP) Q5B4G0 (/IMP)
Regulation of secondary metabolite biosynthetic process GO:1900376
Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process.
2 Q5B4G0 (/IMP) Q5B4G0 (/IMP)
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
1 O94667 (/ISO)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 P53064 (/IDA) P53064 (/IDA) P53064 (/IDA) P53064 (/IDA) Q5B4G0 (/IDA) Q5B4G0 (/IDA)
Cdc73/Paf1 complex GO:0016593
A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
4 P53064 (/IPI) P53064 (/IPI) P53064 (/IPI) P53064 (/IPI)
Transcriptionally active chromatin GO:0035327
The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed.
4 P53064 (/IDA) P53064 (/IDA) P53064 (/IDA) P53064 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O94667 (/HDA)
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