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CATH Superfamily 3.90.660.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: spermine oxidase isoform X2

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Spermine oxidase. [EC: 1.5.3.16]
Spermine + O(2) + H(2)O = spermidine + 3-aminopropanal + H(2)O(2).
  • The enzyme from Arabidopsis thaliana (AtPAO1) oxidizes norspermine to norspermidine with high efficiency.
  • The mammalian enzyme, encoded by the SMOX gene, is a cytosolic enzyme that catalyzes the oxidation of spermine at the exo (three-carbon) side of the tertiary amine.
  • No activity with spermidine.
  • Weak activity with N(1)-acetylspermine.
  • Differs in specificity from EC 1.5.3.13, EC 1.5.3.14, EC 1.5.3.15 and EC 1.5.3.17.
  • Formerly EC 1.5.3.11, EC 1.5.3.n1, EC 1.5.3.n2, EC 1.5.3.n3 and EC 1.5.3.n5.
 4 Q3UPW5 Q3UPW5 Q99K82 Q99K82