View in Gene3D

CATH Superfamily 3.90.660.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 38: Polyamine oxidase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Non-specific polyamine oxidase. [EC: 1.5.3.17]
(1) Spermine + O(2) + H(2)O = spermidine + 3-aminopropanal + H(2)O(2). (2) Spermidine + O(2) + H(2)O = putrescine + 3-aminopropanal + H(2)O(2). (3) N(1)-acetylspermine + O(2) + H(2)O = spermidine + 3-acetamidopropanal + H(2)O(2). (4) N(1)-acetylspermidine + O(2) + H(2)O = putrescine + 3-acetamidopropanal + H(2)O(2).
  • The non-specific polyamine oxidases may differ from each other considerably.
  • The enzyme from Saccharomyces cerevisiae shows a rather broad specificity and also oxidizes N(8)-acetylspermidine.
  • The enzyme from Ascaris suum shows high activity with spermine and spermidine, but also oxidizes norspermine.
  • The enzyme from Arabidopsis thaliana shows high activity with spermidine, but also oxidizes other polyamines.
  • The specific polyamine oxidases are classified as EC 1.5.3.13, EC 1.5.3.14, EC 1.5.3.15 and EC 1.5.3.16.
  • Formerly EC 1.5.3.11, EC 1.5.3.n1, EC 1.5.3.n2 and EC 1.5.3.n4.
 16 A0A0L8VJV5 A0A0L8VJV5 A0A0L8VJV5 A0A0L8VJV5 B3LLS1 B3LLS1 B3LLS1 B3LLS1 N1P5C2 N1P5C2
(6 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...