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CATH Superfamily 3.90.550.50

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: Hexosyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase. [EC: 2.4.1.313]
UDP-N-acetyl-alpha-D-galactosamine + 3-O-(N-acetyl-beta-D-glucosaminyl- (1->4)-alpha-D-mannosyl)-L-threonyl-[protein] = UDP + 3-O-(N-acetyl-beta- D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D- mannosyl)-L-threonyl-[protein].
  • The human protein is specific for UDP-N-acetyl-alpha-D-galactosamine as donor.
  • The enzyme is involved in the formation of a phosphorylated trisaccharide on a threonine residue of alpha-dystroglycan, an extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains.
 8 A0A1L8G8D4 A0A1L8G8D4 Q502B3 Q5M900 Q6NRQ1 Q6NRQ1 Q8BG28 Q8NCR0
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