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CATH Superfamily 3.90.25.10

UDP-galactose 4-epimerase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
UDP-galactose 4-epimerase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 37: NAD-dependent epimerase/dehydratase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
DTDP-4-dehydro-6-deoxyglucose reductase. [EC: 1.1.1.266]
dTDP-alpha-D-fucopyranose + NAD(P)(+) = dTDP-4-dehydro-6-deoxy-alpha-D- glucose + NAD(P)H.
  • The enzymes from the Gram-negative bacteria Actinobacillus actinomycetemcomitans and Escherichia coli O52 are involved in activation of fucose for incorporation into capsular polysaccharide O-antigens.
  • The enzyme from the Gram-positive bacterium Anoxybacillus tepidamans (Geobacillus tepidamans) is involved in activation of fucose for incorporation into the organism's S-layer.
  • The enzyme from E.coli O52 has a higher catalytic efficiency with NADH than with NADPH.
 1 Q6E7F2
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