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CATH Superfamily 3.90.230.10

Creatinase/methionine aminopeptidase superfamily

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Creatinase/methionine aminopeptidase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Methionine aminopeptidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Metalloaminopeptidase activity GO:0070006
Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
 166 P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA)
(156 more)
Ferrous iron binding GO:0008198
Interacting selectively and non-covalently with ferrous iron, Fe(II).
 155 P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA)
(145 more)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
 11 P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA)
(1 more)
Nickel cation binding GO:0016151
Interacting selectively and non-covalently with nickel (Ni) cations.
 11 P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA)
(1 more)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
 11 P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA)
(1 more)
Cobalt ion binding GO:0050897
Interacting selectively and non-covalently with a cobalt (Co) ion.
 11 P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA)
(1 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein initiator methionine removal GO:0070084
The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein.
 155 P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA)
(145 more)
Methionine metabolic process GO:0006555
The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
 11 P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA)
(1 more)
Protein initiator methionine removal involved in protein maturation GO:0035551
Removal of the initiating methionine or formylmethionine residue from a protein that contributes to protein maturation, the attainment of the full functional capacity of a protein.
 11 P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA) P9WK19 (/IDA)
(1 more)
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
 9 Q9KPV1 (/ISS) Q9KPV1 (/ISS) Q9KPV1 (/ISS) Q9KPV1 (/ISS) Q9KPV1 (/ISS) Q9KPV1 (/ISS) Q9KPV1 (/ISS) Q9KPV1 (/ISS) Q9KPV1 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 155 P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA) P0AE18 (/IDA)
(145 more)